Should We Worried While Decompressing Deeply Seated Brain Tumors Under IONM, Intraoperative Neurophysiological Monitoring . Deeply seated brain tumors

Corticospinal Motor tract monitoring during insular glioma surgery, Deeply Seated Brain Tumors

Insular is distinct lobe of the brain  , deeply seated  brain tumors are located within the cortex .This structure grossly observed deep to the insular operculum which formed by the parietal frontal and temporal lobes. If Glioma involving eloquent areas of the brain ,  equal consideration should be given to maintain supramaximal extent of  resection , to prevent neurological function .

 . Intraoperative neurophysiological monitoring is  effective and admirable approach  .

Surgical approach, Deeply Seated Brain Tumors.

Resection of such a  glioma  tumor if its involving eloquent areas has  an real challenge in surgical treatment to maintain quality of life means patient should  walk and talk post surgery.

Neuro Navigation with Diffuse Tensor Imaging (DTI)

The  role of this imaging technique is virtual to determine the tract , but only  lack  if brain shifts . 

Brain shift during surgery which cause by.

  • CSF Loss .
  • Tumor Resection .
  • Surgical Retraction .
  • Gravity.
  • White matter tract shift at 8-15 millimeter (mm) .

Role of Subcortical corticospinal tract Mapping  and why is it needed ?

What can be done to prevent motor function while decompressing this type deeply seated Motor Eloquent Brain Tumors.

  1. Removing the last deepest  part of tumor near an eloquent area potentially puts neurological function at risk.
  2. Therefore key concept is maximal safe resection. 

What can be done .{Deeply Seated Brain Tumors}

.Continuous dynamic mapping with suction probe.

Isolated standard suction  stimulator  probe ( monopolar)  can be use for subpial dissection and simultaneous stimulation at every site and during every step of the tumor excision.

Technique to map the CST.{Deeply Seated Brain Tumors}

Parameters .

Short  train with five  biphasic pulses with Inerstimulus  interval (ISI) at 2-3 or 3-4 millisecond and 500 microsecond pulse width .  Intensity of current can be  start from 10-12 milliampere  and stop  up to 6-5 milliamps  , Benefit of especially this train of five pulses parameter does not provoke seizure .

Conclusion.

  1. The stimulation intensity of 5 mA indicates the proximity of the probe to the CST by less than 5 millimeters ,means surgeon has to  preserve those functional neural structures  during dissection of tumor , or  otherwise patient can reveal with new  neurological motor function deficit.
  2. Feeding artery will be preserve detection of the Vascular injury is not possible with the Subcortical Mapping Technique.
  3. The threshold can be decreased up to 3 milliampere  in low grade tumors.

Reference.

Related to this article.

https://neurointraoperative.com/wp-admin/post.php?post=1687&action=edit

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057198

  • Why neurosurgeon get worry while decompressing deeply seated tumors, like globus pallidus (GP), caudate nucleus, insular glioma etc?.
  • A- Most of the time injury of CST fibers.
  • What exactly does IONM in these type of cases?.
  • A-Subcortical motor tract mapping in real time.
  • Can we use random parameters?.
  • A-No because others [parameters] not very much useful and possibility of seizure.
  • Why we use only cathodic stimulation for subcortical mapping?.
  • A-Because here directly dealing with axon .
  • Which form of square pulses will be preferable, to avoid current deposition?.
  • A-Biphasic pulses are safe for CNS tissue.

8 thoughts on “Should We Worried While Decompressing Deeply Seated Brain Tumors Under IONM, Intraoperative Neurophysiological Monitoring . Deeply seated brain tumors”

    • Posterior edge of insular region contains major neural structure which is corticospinal tract means control our motor function, so SSEP
      not very important rather than motor.
      MEP is not possible these types of cranium surgery because in expose brain difficult to put corkscrew electrode , so direct cortical and subcortical eloquent cortex mapping is useful.

      Reply

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